Researches on Ganoderma Lucidum anti-tumor functions began in the 1970s. It represents the most far reaching and in depth studies involving the pharmacological actions of this miraculous herb.
Today, it has become clearly evident that Ganoderma Lucidum can contribute in no small way to the treatment of cancer. The major health benefits of this herb are manifested in "subduing tumor growth" and "restraining the spread of cancer cells".
When used in combination with western medication, Ganoderma not only helps to achieve better therapeutic results. It also considerably reduced side effects caused by conventional medication.
Of course, Ganoderma application in cancer treatment does not assure complete elimination of cancer cells in all cases.
However many research findings indicated that this fungus exhibits a more impressive efficacy in preventing onset of cancer than resisting cancer growth. The dosages needed in the former case are much lesser than in the latter case.
A research conducted by Professor Ching-Hua Su of Taipei Medical College has shed some encouraging lights on Ganoderma anti cancer efficacy.
In his experiment, a number of mice were injected with 1mg per kg body weight of purified Ganoderma polysaccharides every day for a week. Then, they were all injected with cancerous cells.
The experiment result showed the number of cancerous cells remained in the bodies of this treated mice group was only 4% of that of the control group, mice without the preventive treatment.
This clearly showed that Ganoderma is not only effective in preventing the onset of cancer but also aids in discouraging cancerous cells spread. It also contributes to lowering the risks of relapse thereafter.
Interestingly, the in vitro (outside the body) experiment carried out by Professor Lin Zhi Bin of Beijing Medical College also points to the same results.
In his experiment, Professor Lin cultured phagocytes (which are capable of gulping down intruders and various harmful entities found in the body) or spleen cells (the centers that produce immunity cells) together with Ganoderma Lucidum polysaccharides for 24 hours.
When he mixed the culture with human leukocytes (HL-60), he discovered that the culture could significantly subdue the proliferation of leukocytes and gradually exterminate them.
From cellular, animal or in vitro experiments, we can arrive at a conclusion. Through primarily "fortifying the immune system" and without harming normal cells, Ganoderma Lucidum could reinforce our immune defense abilities in identifying and wiping out abnormal cells.
This includes revitalizing phagocytes, neutrophils, natural killer or NK cells, T-cells, antibodies, etc. and encouraging their proliferation.
Apart from that, it also revitalizes dendron cells as well as enhances the secretion of corresponding hormones of immunity cells, such as Tumor Necrosis Factor-alpha, Interleukin-1, Interleukin-2, Interleukin-6, and Interferon Gamma and revitalizes them.
In this respect, the primary active constituent is Ganoderma polysaccharides.
As Ganoderma Lucidum efficacy in prevention and treatment of tumor stems from its ability to fortify immune system, it is beneficial in guarding against practically all sorts of cancer diseases.
Clinical researches have shown that the use of Ganoderma Lucidum with surgical removal, radio therapy, and chemo therapy are effective in improving the conditions of stomach cancer, lung cancer, liver cancer, colon cancer, pancreatic cancer, kidney cancer, prostate cancer, breast cancer, ovary cancer, uterus cancer and blood cancer (leukemia).
A recent animal experiment conducted in Japan indicated that Ganoderma Lucidum is helpful in subduing the proliferation and lesion or pathological changes of cancer cells in colon.
An in vitro experiment carried out by Clarian Health Partners, a prominent hospital in US, also confirmed that Ganoderma Lucidum is capable of subduing the vitalities of breast cancer cells and prostate cancer cells.
During the International Edible Fungus Research Convention held in Miami, USA early March 2005, research paper submitted by a Japanese researcher also points Ganoderma benefits for prostate problems.
It stated that Triterpenes in Ganoderma Lucidum are helpful in prevention and treatment of prostate cancer and prostate enlargement through its ability in subduing the vitality of 5 alpha - reductase.
Extracted from the 24th issue of medical journal "Ganoderma"
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